Comerica Park is located at 2100 Woodward Ave, just south of I-75 (Fisher Freeway) and directly across the street from the Fox Theatre.

From Southwest Detroit, Downriver suburbs, and Toledo:
Follow northbound I-75 (Fisher Freeway) past the Old Tiger Stadium to the Grand River Avenue Exit (exit 50). Proceed on the I-75 service drive across Grand River Avenue, and continue east to Woodward Avenue. Turn right on Woodward Avenue. Comerica Park is located on the east side.

From Ann Arbor, Dearborn, Inkster, Wayne, and Western Suburbs:
Follow eastbound I-94 (Ford Freeway) to eastbound I-96 (Jeffries Freeway). Proceed on I-96 to northbound I-75 service drive across Grand River Avenue (exit 50). Proceed on the I-75 service drive across Grand River Avenue, and continue east to Woodward Ave. Turn right on Woodward Ave. Comerica Park is located on the east side.

From Lansing, Livonia, Westland, Redford Township and Northern Wayne and Western Oakland County Suburbs:
(From Lansing, Novi area, take I-96 east to I-275 south). Take I-96 eastbound to northbound I-75 (Fisher Freeway). Exit at the Grand River Avenue Exit (exit 50). Proceed on the I-75 service drive across Grand River Avenue, and continue east to Woodward Avenue. Turn right on Woodward Avenue. Comerica Park is located on the east side.

From Bloomfield, Farmington Hills, Central and Northwestern Detroit and Oakland County Suburbs:
Follow southbound M-10 (Lodge Freeway) to the Grand River Avenue Exit. Follow the trailblazer signs to the I-75 eastbound service drive. Proceed on the I-75 service drive across Grand River Avenue, and continue east to Woodward Ave. Turn right on Woodward Ave. Comerica Park is on the east side.

From Pontiac, Troy, Northern Detroit Suburbs:
Follow southbound I-75 (Chrysler Freeway) to the Mack Avenue Exit. Turn right on Mack Avenue and proceed to Woodward Avenue. Turn left (south) on Woodward Avenue and follow to Comerica Park (1 mile). If you miss the Mack Avenue Exit you can proceed on I-75 (Chrysler Freeway) to either southbound I-75 (Fisher Freeway) or I-375 and follow the Comerica Park signs.

From Mt. Clemens, Grosse Pointe, Port Huron and the East Site Suburbs:
Follow westbound I-94 (Ford Freeway) to southbound I-75 (Chrysler Freeway). Proceed to the Mack Avenue Exit. Turn right on Mack Avenue and proceed to Woodward Avenue. Turn left (south) on Woodward Avenue and follow to Comerica Park (1 mile). If you miss the Mack Avenue Exit, you can proceed on I-75 (Chrysler Freeway) to either southbound I-75 (Fisher Freeway or I-375 and follow the Comerica Park signs.

From Windsor, Canada:
From Ambassador Bridge:
Take I-75 North to exit 50 (Grand River Ave.). Stay straight on the I-75 service drive. Turn right onto Woodward. Comerica Park is on the left.

From Windsor/Detroit Tunnel:
Turn right on to Jefferson heading East. Get in the far left hand lane and do a loop around so you are headed West on Jefferson. Take Jefferson to Woodward and turn right, heading North. Comerica Park is about 10 blocks ahead on the right.